The man had just purchased the motorbike from Camperdown and was heading to Melbourne along the Foxhow Road, when police believe he lost concentration and hit the gravel.
The man was wearing a helmet, but no other protective clothing. It is believed that he has broken his pelvis, with multiple other injuries.
Camperdown police attended along with road ambulances and the air ambulance was directed in to land at the Cressy football ground.
Police made a statement urging motorcyclists to wear protective gear, stating if the man had not have been wearing his helmet, they could've been at the scene of a fatality.